KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF4B
All Species:
35.15
Human Site:
S291
Identified Species:
51.56
UniProt:
Q2VIQ3
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2VIQ3
NP_001092763.1
1234
140035
S291
S
F
V
P
Y
R
D
S
K
L
T
R
L
L
Q
Chimpanzee
Pan troglodytes
XP_518055
1227
139177
S291
S
F
V
P
Y
R
D
S
K
L
T
R
L
L
Q
Rhesus Macaque
Macaca mulatta
XP_001084213
1234
139742
S291
G
F
V
P
Y
R
D
S
K
L
T
R
L
L
Q
Dog
Lupus familis
XP_549061
1234
139874
S292
G
F
V
P
Y
R
D
S
K
L
T
R
L
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
P33174
1231
139533
S292
N
F
V
P
Y
R
D
S
K
L
T
R
L
L
Q
Rat
Rattus norvegicus
Q7M6Z5
1394
158861
A296
S
H
V
P
Y
R
D
A
K
I
T
R
L
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90640
1225
138905
S293
G
F
V
P
Y
R
D
S
K
L
T
R
L
L
Q
Frog
Xenopus laevis
Q91784
1226
138905
S292
G
F
V
P
Y
R
D
S
K
L
T
R
L
L
Q
Zebra Danio
Brachydanio rerio
Q58G59
1363
154819
S302
T
H
I
P
Y
R
D
S
K
I
T
R
I
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
Honey Bee
Apis mellifera
XP_395595
1064
123475
S274
I
S
Q
L
G
E
G
S
S
T
T
Y
V
G
Y
Nematode Worm
Caenorhab. elegans
P46873
699
78760
Sea Urchin
Strong. purpuratus
P46872
699
78679
Poplar Tree
Populus trichocarpa
XP_002302432
1055
118553
I251
R
S
H
A
I
F
T
I
T
L
E
Q
M
R
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_200901
1294
145204
S315
G
H
V
P
Y
R
D
S
K
L
T
R
L
L
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
E144
S
Y
M
E
I
Y
M
E
R
I
R
D
L
L
A
Conservation
Percent
Protein Identity:
100
97.9
90.9
91
N.A.
83.6
26.4
N.A.
N.A.
71.3
66.6
25.1
N.A.
27.2
36.8
25.6
27.4
Protein Similarity:
100
98.8
94
94.7
N.A.
90.3
47.2
N.A.
N.A.
83.7
80.1
44.1
N.A.
41
55.8
38.5
38.4
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
73.3
N.A.
N.A.
93.3
93.3
60
N.A.
0
13.3
0
0
P-Site Similarity:
100
100
93.3
93.3
N.A.
100
93.3
N.A.
N.A.
93.3
93.3
93.3
N.A.
0
20
0
0
Percent
Protein Identity:
31.9
N.A.
N.A.
30.6
N.A.
26.6
Protein Similarity:
50
N.A.
N.A.
49.1
N.A.
44
P-Site Identity:
6.6
N.A.
N.A.
86.6
N.A.
20
P-Site Similarity:
26.6
N.A.
N.A.
86.6
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
63
0
0
0
0
7
0
0
0
% D
% Glu:
0
0
0
7
0
7
0
7
0
0
7
0
0
0
0
% E
% Phe:
0
44
0
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
32
0
0
0
7
0
7
0
0
0
0
0
0
7
0
% G
% His:
0
19
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
7
0
13
0
0
7
0
19
0
0
7
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
63
0
0
0
0
0
19
% K
% Leu:
0
0
0
7
0
0
0
0
0
57
0
0
63
69
0
% L
% Met:
0
0
7
0
0
0
7
0
0
0
0
0
7
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
63
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
50
% Q
% Arg:
7
0
0
0
0
63
0
0
7
0
7
63
0
7
0
% R
% Ser:
25
13
0
0
0
0
0
63
7
0
0
0
0
0
0
% S
% Thr:
7
0
0
0
0
0
7
0
7
7
69
0
0
0
0
% T
% Val:
0
0
57
0
0
0
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
63
7
0
0
0
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _